Academic Journal Publications

Soliton-Based Signaling Communication and Supermolecular Nano-complex by DDMC/PTX in Tumor Microenvironment
BioNanoSci. (2023)

Soliton Dynamics and DDMC/sncRNAs Complex for Epigenetic Change to Normal Cells in TME
BioNanoSci. (2023)

Consideration with “Intratumoral gene therapy versus intravenous gene therapy for distant metastasis control with DDMC non-viral vector-P53”
Gene Therapy. volume 29, pages 313-315 (2022)

The full recovery of mice (Mus Musculus C57BL/6 strain) from virus-induced sarcoma after treatment with a complex of DDMC delivery system and sncRNAs
Non-coding RNA Research, 2019, In Press

A robust control system for targeting melanoma by a supermolecular DDMC/paclitaxel complex
Integrative Biology, 2018,10, 549-554!divAbstract

Supermolecular drug challenge to overcome drug resistance in cancer cells
Drug Discovery Today, 2018

The Disappeared Cancer Cell by SncRNAs: Application of DDMC Vector/SncRNAs Complex for Transformation of Cancer Cells into Non-cancerous Cells
Journal of Nanomedicine & Biotherapeutic Discovery, 2018, 8:1

Small non-coding RNAs as regulators of structural evolution and carcinogenesis.
Non-coding RNA Research, Volume 2, Issue 2, June 2017, Pages 88-92

Toxicity and Transfection Efficiency of New Non-Viral Delivery Systems for Small Non-Coding RNAs: Amphiphilic Poly(N-Vinylpyrrolidone) and Diethylaminoethyl-Dextran-Methacrylic Acid Methyl Ester Copolymer
Advanced Science, Engineering and Medicine, 9, (6), 426-431(2017)

Joint Action of the Nano-sized System of Small Non-coding RNAs with DDMC Vector and Recombinant IL-7 Reprograms A-549 Lung Adenocarcinoma Cells into CD4+ Cells.
Immunotherapy (Los Angel) 3: 137. doi:10.4172/2471-9552.1000137 (2017)

Complex of Small Non-coding RNAs piR-30074 and Antago-miR-155 and miR-125b with DDMC Carrier Transforms Girardi Heart Cells into CD4+ Cells
Journal of Cancer and Tumor International, ISSN: 2454-7360,Vol.: 4, Issue.: 4 (2016)

Medicinal facilities to B16F10 melanoma cells for distant metastasis control with a supramolecular complex by DEAE-dextran-MMA copolymer/paclitaxel
Drug Delivery and Translational Research. 5:38-50 (2015)

Anticancer efficacy of a supramolecular complex of a 2-diethylaminoethyl-dextran-MMA graft copolymer and paclitaxel used as an artificial enzyme
Beilstein J. Nanotechnol. 2014, 5, 2293-2307. (2014)

Allosteric Facilities as Artificial Enzymes to Cancer Cell of Supramolecular Complex by Polymer/Anti-Cancer Agents
J Nanomedine Biotherapeutic Discov 4:e127 (2014)

Intratumoral gene therapy versus intravenous gene therapy for distant metastasis control with 2-Diethylaminoethyl-Dextran Methyl Methacrylate Copolymer Non-Viral Vector-p53
Gene Therapy 21, 158-167 (2014)

Anti-cancer facility by nano-particle using supramolecular complex by DEAE-dextran-MMA graft copolymer/paclitxel as an artificial enzyme.
Processing Reports of the Faculty of Engineering Oita University 2014; 61:17-30.

Dextran Graft Copolymers: Synthesis, Properties and Applications
Polysaccharide Based Graft Copolymers pp 205-269, Springer(2013)

Supramolecular Targeting of B16F10 Melanoma Cells With Nanoparticles Consisting of a DEAE-Dextran-MMA Copolymer-Paclitaxel Complex
J Nanomed Biotherapeut Discov 2:5(2012)

Supramolecular Facilities to Melanoma Cells B16F10 with Nanoparticles of a DEAE-Dextran-MMA Copolymer-Paclitaxel Complex
J Nanomed Nanotechol S:5(2012)

Mechanism of the Introduction of Exogenous Genes into Cultured Cells Using DEAE-Dextran-MMA Graft Copolymer as a Non-Viral Gene Carrier. II. Its Thixotropy Property
J Nanomedic Nanotechnol 2:105(2011)

Transfection of foreign genes into cultured cells using novel DEAE-dextran cop olymer as a non-viral gene carrier.

DEAE-Dextran and DEAE-Dextran-MMA Graft Copolymer for Nanomedicine
Polymers Research Journal vol. 3, issue 3-4,415-453(2010)

Advances in Nanotechnology, Volume 3 Chapter 11(2010)

DEAE-Dextran-MMA Graft Copolymer for Non-viral Delivery of DNA,
Jorgenson, Lene Nielson, Hanne Morck, Ed., Delivery Technologies for Biophar maceuticals,John Wiley & Sons,West Sussex UK(November 2009)

Mechanism of Introducing ExogenousGenes into Cultured Cells Using DEAE-Dextran- MMA Graft Copolymer as Non-Viral Gene Carrier,
Molecules 14, 2669-2683 (2009).

Characteristics of 2-diethylaminoethyl(DEAE)-dextran-MMA graft copolymer as a non-viral gene carrier.
Nanomedicine: Nanotechnology, Biology, and Medicine, 3:184-191,2007.

A novel vector of 2-diethylaminoethyl(DEAE)-dextran-MMA graft copolymer for no n-viral gene delivery.
The 13th Annual Meeting of JSGT - 2007,at the International Conference Hall (Aichi Cancer Center) in Nagoya,June 28-30, 2007, Abstr. 074.

2-diethylaminoethyl(DEAE)-Dextran-MMA graft copolymer for nonviral gene delivery vector.
Bulletin of the Research Center of Environmental Science and Technology,
NIppon Bunri University (Vol.5 2006)

Synthesis and characterization of 2-diethyl-aminoethyl-dextran-methyl methacrylate graft copolymer for nonviral gene delivery vector.
J.Appl. polym. Sci.,(2005)

about gene delivery systems(PDF)

Specification of DDMC Vector(PDF)

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